Role of diffusion-weighted MRI in diagnosis and post therapeutic follow-up of colorectal cancer

Abstract Background The colorectal cancer (CRC) is one of the deadliest cancers in world. Local tumor stage, vascular or lymphatic invasion, and grade are essential for accurate management. main imaging modality initial assessment therapeutic response evaluation CRC magnetic resonance (MRI). purpose this prospective study was to illustrate role diffusion-weighted MRI (DWI) apparent diffusion coefficient (ADC) value grading carcinoma as well its chemotherapy combined chemoradiation. Results Restricted DWI found 37 out 40 patients with sensitivity about 92.5%. In studied group, median ADC 1.21 (min 0.80, max 1.31) average 1.14 ± 0.161. mean poorly differentiated tumors 0.979 × 10 −3 mm 2 /s. moderately 1.112 well-differentiated 1.273 sensitivity, specificity, PPV, NPV, accuracy were higher addition conventional reaching 100%, 80%, 83.3%, 90%, respectively. Conclusion Adding DW yields better diagnostic than using MR alone detection, correlation histologic grade, staging, neoadjuvant chemoradiotherapy locally advanced cancer.